A Comparison of GC-ICP-MS and HPLC-ICP-MS for the Analysis of Organotin Compounds Application
نویسنده
چکیده
An inductively coupled plasma mass spectrometer (ICP-MS) was used as a detector for gas chromatography (GC) and high performance liquid chromatography (HPLC) analysis of organotin compounds. ICP-MS is a highly sensitive detector with detection limits in the pg ng range, as well as enabling calibration by isotope dilution mass spectrometry (IDMS). Calibrating using isotopically labeled organotin species reduces measurement uncertainties and leads to greater precision compared to external calibration methods. This application note details the relative merits of the two techniques for the analysis of organotin compounds.
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